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Advances in emerging field of ‘theranostics’ are a game-changer Millions of patients around the globe rely on the regular and timely production of diagnostic and therapeutic isotopes produced in research reactors and accelerator facilities. Image courtesy IAEA. Advances in medical isotope diagnostics and therapy are holding promise for cancer patients, despite challenges facing the nuclear medical field in recent years related to radionuclide production and supply, rising costs, and stricter regulation.

Medical isotopes are radioactive substances used in various diagnostic and therapeutic procedures to treat various types of cancers and other conditions. They are essential for modern medicine, allowing physicians to visualise and target specific organs, tissues and cells in a patient’s body.

Over more than a decade, personalised medicine using nuclear techniques has been gaining pace, allowing doctors to tailor therapies and treatments to the specific needs and physiology of a patient, and to avoid harm to healthy organs or tissues.

According to Sven Van den Berghe, chief executive of Belgium-based isotope producer PanTera, one technique that has seen significant advances is known as theranostics – the term used to describe the combination of using one radioactive drug to diagnose and a second to deliver therapy to treat the main tumour and any metastatic tumours.

Date: Friday, 14 April 2023
Original article: nucnet.org/news/sector-aims-to-tackle-isotope-supply-problems-as-excitement-grows-over-targeted-therapies-4-4-2023

Russia’s BP Konstantinova Petersburg Institute of Nuclear Physics has announced a tender for the development of a core design for the PIK research reactor in Gatchina, RosTender.info reported on 7 July.

Date: Friday, 10 July 2020
Original article: neimagazine.com/news/newstender-announced-to-provide-fuel-for-russias-pik-reactor-8018410

The head of the Atomic Energy Organisation of Iran (AEOI), Ali Akbar Salehi, said on 8 April in a message marking National Nuclear Technology Day that Iran’s nuclear activities were continuing despite the novel coronavirus outbreak and continuing US sanctions.

Date: Wednesday, 15 April 2020
Original article: neimagazine.com/news/newsiran-pushes-ahead-with-nuclear-development-despite-pandemic-restrictions-7871976

The ETRR-2 research reactor in Egypt. Photo courtesy Rosatom. Novosibirsk Chemical Concentrates Plant (NCCP) and the Egyptian Atomic Energy Authority have signed a 10-year contract for Russia to supply low-enriched uranium (LEU) for the ETRR-2 research reactor.

Russia’s Tvel nuclear fuel company, of which NCCP is a subsidiary, said the contract is a logical follow-up to a number of contracts for the shipment of fuel components to Egypt in recent years.

The Argentinian-designed multipurpose ETRR-2, Egypt’s only reactor, uses uranium fuel with an enrichment of 19.75%. The reactor is used for research in particle physics, materials engineering, and the production of stable isotopes.

Tvel, a subsidiary of Russian state nuclear corporation Rosatom, said it considers Egypt an important and promising market. The company already has a contract for nuclear fuel supplies to the future El Dabaa nuclear station in the north of the African country. The contract covers supplies to all four power units of El Dabaa during the facility’s entire operational lifetime.

Date: Tuesday, 07 April 2020
Original article: nucnet.org/news/russia-to-supply-leu-for-etrr-2-research-reactor-4-1-2020

Ghana has commissioned three new nuclear faciliies – the Low-Enriched Uranium Core Research Reactor Facility, the International Miniature Neutron Source Reactor Training Facility and the Radiological and Medical Science Research Institute Laboratories building at the Scientific Research and Development Institution of the Ghana Atomic Energy Commission (GAEC).

Date: Tuesday, 13 August 2019
Original article: neimagazine.com/news/newsghana-commissions-three-nuclear-facilities-7366131

The US Department of Energy’s National Nuclear Security Administration (DOE/NNSA) said on 20 February that it had completed its evaluation of applications submitted in response to a funding opportunity for the production of molybdenum-99 (Mo-99) without the use of highly enriched uranium (HEU).

Date: Tuesday, 26 February 2019
Original article: neimagazine.com/news/newsus-to-fund-four-companies-to-produce-mo-99-without-use-of-heu-7008435

Canadian Nuclear Laboratories (CNL) announced on 2 April that isotope production reactor the National Research Universal (NRU) at the Chalk River site had been permanently shut down. It will now be placed into a "state of storage" prior to decommissioning. The reactor, which produced about 40% of world supply of molybdenum-99 (Mo-99), ceased production in October 2016, since when it has remained on standby "in case of a significant shortage which could not be mitigated by other means". Research reactors in Australia, Europe, Russia and South Africa have since met demand.

Date: Friday, 06 April 2018
Original article: neimagazine.com/news/newscanada-permanently-closes-nru-research-reactor-6107149


Russia has removed highly-enriched irradiated liquid nuclear fuel from Uzbekistan's IIN-3M research reactor. Moscow-based Sosny, which develops technologies for the preparation of used nuclear fuel for reprocessing or storage, said the shipment was completed on 24 September.

Date: Wednesday, 30 September 2015
Original article: neimagazine.com/news/newsfuel-removal-paves-way-for-decommissioning-of-uzbek-research-complex-4682488


Construction of the world's most powerful multi-purpose fast neutron research reactor (MBIR) has officially started at the Research Institute of Atomic Reactors (NIIAR) in Dimitrovgrad, in Russia's Ulyanovsk region. The project is being implemented as part of the federal targeted-development programme called "New-Generation Nuclear Energy Technologies for 2010-2015 and up to 2020". The reactor is scheduled for start-up in 2020. The thermal power of the new sodium-cooled reactor will be 150MWt.

Date: Wednesday, 16 September 2015
Original article: neimagazine.com/news/newsrussia-begins-construction-of-mbir-4671316

An international effort has resulted in the successful removal of the all the remaining highly enriched uranium (HEU) from Hungary.

The final 49.2 kilograms of HEU was removed from Hungary via three secure air shipments over a six-week period, the US Department of Energy said 4 November.

The multi-year effort was coordinated between Hungary, the United States, the Russian Federation, and the International Atomic Energy Agency (IAEA).

The four participants also returned 190 kilograms of HEU from Hungary to Russia via three shipments in 2008, 2009, and 2012.

"The material will be transported to Russia where it will be downblended into low enriched uranium (LEU) for use in nuclear power reactors," the US National Nuclear Security Administration (NNSA) said.

The recent quantity of HEU removed from Hungary was "enough for nine nuclear weapons," according to NNSA.

Hungary originally procured the HEU from Russia for use in scientific applications in the Budapest Research Reactor at Hungary's Atomic Energy Research Institute. In 2009, NNSA and Hungarian scientists successfully converted the reactor from HEU to LEU use, allowing for the elimination of Hungary's entire HEU inventory.

Date: Tuesday, 05 November 2013
Original article: neimagazine.com/news/newshungary-becomes-heu-free